Start with the high-friction differences
When two listings share a similar title, start by comparing the details that affect whether you would actually take the role: location, work arrangement, attendance expectations, compensation wording, schedule, contract type, and route to apply. These differences usually matter more than broad keyword overlap. A job that looks promising in title alone can still be a poor target if the commute, contract terms, or source path make it a weak fit for your situation.
This is also the fastest way to reduce noise. Instead of reading every line with equal weight, compare the factors that would change your actual decision first. If one role already loses on location, schedule, or pay clarity, you may not need to spend additional time tailoring your resume for it.